Jamie Lee Curtis will head up a huge evening of celebrities and song at the John Wayne Cancer Institute What A Pair! benefit show.
Celebrity women will pair up and perform Broadway style to raise funds for breast cancer research.
Jessica Biel, Kirstin Bell, Marg Helgenberger, Katey Sagal and Rita Wilson have all been involved in past years.
The audience can celebrate with the cast after the show at the VIP after-party where there will be a boutique-style silent auction.
The John Wayne Cancer Institute What A Pair! benefit show is on June 8.